Acrux developed Evamist® (estradiol transdermal spray) which is  used in women to treat moderate to severe hot flushes commonly associated with menopause.

The fast-drying spray delivers a low dose of estradiol, resulting in therapeutic blood levels similar to the exposure range for other approved estrogen products. Sprays should be allowed to dry for approximately 2 minutes before covering the site with clothing.

Evamist® spray is licensed to Padagis (formerly named Perrigo) and has been for sale in the United States since 2009.

Refer to the Prescribing Information for further information on the product.